- GEORGE CLOONEY / Michael Clayton – “Michael Clayton” (Warner Bros. Pictures)
- DANIEL DAY-LEWIS / Daniel Plainview – “There Will Be Blood” (Paramount Vantage)
- RYAN GOSLING / Lars Lindstrom – “Lars And The Real Girl” (Sidney Kimmel Entertainment)
- EMILE HIRSCH / Christopher McCandless– “Into The Wild” (Paramount Vantage)
- VIGGO MORTENSEN / Nikolai – “Eastern Promises” (Focus Features)
Outstanding Performance by a Female Actor in a Leading Role
- CATE BLANCHETT / Queen Elizabeth I – “Elizabeth: The Golden Age” (Universal Pictures)
- JULIE CHRISTIE / Fiona – “Away From Her” (Lionsgate)
- MARION COTILLARD / Edith Piaf – “La Vie En Rose” (Picturehouse)
- ANGELINA JOLIE / Mariane Pearl – “A Mighty Heart” (Paramount Vantage)
- ELLEN PAGE / Juno MacGuff – “Juno” (Fox Searchlight Pictures)
Outstanding Performance by a Male Actor in a Supporting Role
- CASEY AFFLECK / Robert Ford – “The Assassination of Jesse James By The Coward Robert Ford” (Warner Bros. Pictures)
- JAVIER BARDEM / Anton Chigurh – “No Country For Old Men” (Miramax Films)
- HAL HOLBROOK / Ron Franz – “Into The Wild” (Paramount Vantage)
- TOMMY LEE JONES / Ed Tom Bell – “No Country For Old Men” (Miramax Films)
- TOM WILKINSON / Arthur Edens – “Michael Clayton” (Warner Bros. Pictures)
Outstanding Performance by a Female Actor in a Supporting Role
- CATE BLANCHETT / Jude – “I’m Not There” (The Weinstein Company)
- RUBY DEE / Mama Lucas – “American Gangster” (Universal Pictures)
- CATHERINE KEENER / Jan Burres – “Into The Wild” (Paramount Vantage)
- AMY RYAN / Helene McCready – “Gone Baby Gone” (Miramax Films)
- TILDA SWINTON / Karen Crowder – “Michael Clayton” (Warner Bros. Pictures)
Outstanding Performance by a Cast in a Motion Picture
3:10 TO YUMA (Lionsgate)
- CHRISTIAN BALE / Dan Evans
- RUSSELL CROWE / Ben Wade
- PETER FONDA / Byron McElroy
- GRETCHEN MOL / Alice Evans
- DALLAS ROBERTS / Grayson Butterfield
- VINESSA SHAW / Emmy Roberts
- BEN FOSTER / Charlie Prince
- ALAN TUDYK / Doc Potter
- LOGAN LERMAN / Will Evans
- ARMAND ASSANTE / Dominic Cattano
- JOSH BROLIN / Detective Trupo
- RUSSELL CROWE / Richie Roberts
- RUBY DEE / Mama Lucas
- CHIWETEL EJIOFOR / Huey Lucas
- IDRIS ELBA / Tango
- CUBA GOODING, JR. / Nicky Barnes
- CARLA GUGINO / Laurie Roberts
- JOHN HAWKES / Freddie Spearman
- TED LEVINE / Lou Toback
- JOE MORTON / Charlie Williams
- LYMARI NADAL / Eva
- JOHN ORTIZ / Javier J. Rivera
- RZA / Moses Jones
- YUL VAZQUEZ / Alfonse Abruzzo
- DENZEL WASHINGTON / Frank Lucas
- NIKKI BLONSKY / Tracy Turnblad
- AMANDA BYNES / Penny Pingleton
- PAUL DOOLEY / Mr. Spritzer
- ZAC EFRON / Link Larkin
- ALLISON JANNEY / Prudy Pingleton
- ELIJAH KELLEY / Seaweed
- JAMES MARSDEN / Corny Collins
- MICHELLE PFEIFFER / Velma Von Tussle
- QUEEN LATIFAH / Motormouth Maybelle
- BRITTANY SNOW / Amber Von Tussle
- JERRY STILLER / Mr. French
- JOHN TRAVOLTA / Edna Turnblad
- CHRISTOPHER WALKEN / Wilbur Turnblad
- BRIAN DIERKER / Rainey
- MARCIA GAY HARDEN / Billie McCandless
- EMILE HIRSCH / Chris McCandless
- HAL HOLBROOK / Ron Franz
- WILLIAM HURT / Walt McCandless
- CATHERINE KEENER / Jan Burres
- JENA MALONE / Carine McCandless
- KRISTEN STEWART / Tracy Tatro
- VINCE VAUGHN / Wayne Westerberg
- JAVIER BARDEM / Anton Chigurh
- JOSH BROLIN / Llewelyn Moss
- GARRET DILLAHUNT / Wendell
- TESS HARPER / Loretta Bell
- WOODY HARRELSON / Carson Wells
- TOMMY LEE JONES / Ed Tom Bell
- KELLY MACDONALD / Carla Jean Moss